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Becomex Injection IV/IM X 10ml

400.00

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Each ml contains:

Thiamine hydrochloride BP (Vitamin B1)……………………………………………………………..5 mg

Riboflavine sodium-5-phosphate BP (Vitamin B2)………………………………………………..2 mg

Pyridoxine hydrochloride BP (Vitamin B6)………………………………………………………….2 mg

D- Panthenol BP…………………………………………………………………………………………………..3 mg

Nicotinamide………………………………………………………………………………………………………20 mg

INDICATIONS

Vitamin B complex is needed for the proper functioning of almost every process in the body.

Energy Production

Vitamin B1 is needed to help convert carbohydrates into glucose. Vitamin B2 and Vitamin B6 are needed at a cellular level to convert glucose into energy.

Vitamins B6 is essential for amino acid metabolism and is required for the formation of hemoglobin.

A deficiency in any of these B vitamins can lead to decreased energy production, lethargy and fatigue.

Healthy Nervous System

The Vitamin B complex is essential for the healthy functioning of the nervous system.

Vitamin B1 and Vitamin B6 are essential for the regulation and correct functioning of the entire nervous system including brain function.

Good digestion

The Vitamin B Complex is essential for normal digestion, production of hydrochloric acid and to assist in the breakdown of fats, proteins and carbohydrate. Especially vital for good digestion are Vitamin B1, Vitamin B2, and Vitamin B6. A deficiency of any of these B Vitamins can lead to impaired digestion and deficiency of essential nutrients.

PHARMACOKINETICS

Vitamin B1 (Thiamine) is rapidly absorbed following intramuscular administration. It is widely distributed to most body tissues, and appears in breast milk. Amounts in excess of the body’s requirements are excreted in the urine as unchanged thiamine or as metabolites.

Vitamin B2 (Riboflavin) is widely distributed to body tissue; little is stored in the body. Vitamin B2 is excreted in urine, partly as metabolites. Riboflavin crosses the placenta and is excreted in breast milk.

Vitamin B6 is stored mainly in the liver where there is oxidation to 4-pyridoxic acid and other inactive metabolites which are excreted in the urine.

Small amount of Nicotinamide is excreted unchanged in urine following therapeutic dose.

DOSAGE AND ADMINISTRATION

A therapeutic dose of 1 to 2ml daily is recommended.

Parenteral form may be administered by intramuscular (i.m) or slow intravenous (i.v) injection.

SIDE / ADVERSE EFFECTS

Adverse effects seldom occur following administration of thiamine, but hypersensitivity reactions have occurred, mainly after parenteral administration. No adverse effects have been reported with the use of riboflavin. Large doses of riboflavin result in a bright yellow discoloration of the urine which may interfere with laboratory test. Long-term admini- stration of large doses of pyridoxine is associated with the development of severe peripheral neuropathies.

CONTRAINDICATIONS

Hypersensitivity to any component of the formulation.

DRUG INTERACTIONS / PRECAUTIONS

Pyridoxine reduces the effects of levodopa but this does not occur if a dopadecarboxylase inhibitor is also given. Many drugs may alter either the metabolism or bioavailability of pyridoxine, such agents include isoniazide, penicillamine and oral contraceptives.

KEEP OUT OF THE REACH OF CHILDREN!

STORAGE:

Store in a cool place. Protect from light.

PRESENTATION

Becomex Injection is presented in 10 ml vials.

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